MALDI-TOF mass spectrometry: the quantum leap
نویسندگان
چکیده
منابع مشابه
Fish authentication by MALDI-TOF mass spectrometry.
Recent EU directives and regulations for quality control and authentication of food products have prompted the development of new methods for large-scale tests to ensure the protection of consumers. In view of this, an innovative method based on MALDI-TOF mass spectrometry has been developed and successfully applied to fish authentication. Highly specific mass spectrometric profiles from 25 dif...
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24 A method for rapid species identification of ticks may help clinicians predict the disease outcomes 25 of patients with tick bites and may inform the decision as to whether to administer post-exposure 26 prophylactic antibiotic treatment. We aimed to establish a MALDI-TOF MS spectra database based 27 on the analysis of the legs of 6 tick vectors: Amblyomma variegatum, Rhipicephalus sanguineu...
متن کاملPerformances of the MALDI-TOF Mass Spectrometry system
22 23 Rapid and cost-effective MALDI-TOF MS-based systems will replace conventional 24 phenotypic methods for routine identification of bacteria. We report here the first evaluation 25 of the new MALDI-TOF MS-based VITEK MS system in a large clinical microbiology 26 laboratory. This system used an original spectra classifier algorithm and a specific database 27 designed for the identification o...
متن کاملPractical quantitative biomedical applications of MALDI-TOF mass spectrometry.
Matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOFMS) is used to obtain fast and accurate determinations of molecular mass, but quantitative determinations are generally made by other techniques. In this study we illustrate the practical utility of automated MALDI-TOFMS as a tool for quantifying a diverse array of biomolecules covering an extensive molecular...
متن کاملRoutine identification of Nocardia species by MALDI-TOF mass spectrometry.
We here show adequate species identification for bacterial isolates of the genus Nocardia spp. through VITEK mass spectrometry. Application of a specific sample preparation method in combination with a robust matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) database leads to 94% accurate identification to the species level on a set of 164 isolates. The...
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ژورنال
عنوان ژورنال: Clinical Microbiology and Infection
سال: 2010
ISSN: 1198-743X
DOI: 10.1111/j.1469-0691.2010.03380.x